Lahser, Frederick: search on Z-Library

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1

The Combination of Grazoprevir, a HCV NS3/4A Protease Inhibitor, and Elbasvir, a HCV NS5A Inhibitor, Demonstrates a High Genetic Barrier to Resistance in HCV Genotype 1a Replicons

Lahser, Frederick C., Bystol, Karin, Curry, Stephanie, McMonagle, Patricia, Xia, Ellen, Ingravallo, Paul, Chase, Robert, Liu, Rong, Black, Todd, Hazuda, Daria, Howe, Anita Y.M., Asante-Appiah, Ernest

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2016

Language:

english

File:

PDF, 1.11 MB

english, 2016

2

Kinetic Analyses Reveal Potent and Early Blockade of Hepatitis C Virus Assembly by NS5A Inhibitors

McGivern, David R., Masaki, Takahiro, Williford, Sara, Ingravallo, Paul, Feng, Zongdi, Lahser, Frederick, Asante-Appiah, Ernest, Neddermann, Petra, De Francesco, Raffaele, Howe, Anita Y., Lemon, Stanl

Journal:

Gastroenterology

Year:

2014

Language:

english

File:

PDF, 760 KB

english, 2014

3

Antiviral Activity and Resistance Analysis of NS3/4A Protease Inhibitor Grazoprevir and NS5A Inhibitor Elbasvir in Hepatitis C Virus GT4 Replicons

Asante-Appiah, Ernest, Curry, Stephanie, McMonagle, Patricia, Ingravallo, Paul, Chase, Robert, Nickle, David, Qiu, Ping, Howe, Anita, Lahser, Frederick C.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2017

Language:

english

File:

PDF, 671 KB

english, 2017

4

In Vitro Antiviral Profile of Ruzasvir: A Potent and Pan-genotype Inhibitor of HCV NS5A

Asante-Appiah, Ernest, Liu, Rong, Curry, Stephanie, McMonagle, Patricia, Agrawal, Sony, Carr, Donna, Rokosz, Laura, Lahser, Frederick, Bystol, Karin, Chase, Robert, Black, Stuart, Ferrari, Eric, Ingra

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2018

Language:

english

File:

PDF, 1.25 MB

english, 2018

5

A continuous nonradioactive assay for RNA-dependent RNA polymerase activity

Frederick C. Lahser, Bruce A. Malcolm

Journal:

Analytical Biochemistry

Year:

2004

Language:

english

File:

PDF, 193 KB

english, 2004

6

PTC725, an NS4B-targeting compound, inhibits an HCV genotype 3 replicon, as predicted by genome sequence analysis and determined experimentally

Graci, Jason D., Jung, Stephen P., Pichardo, John, Lahser, Frederick, Tong, Xiao, Gu, Zhengxian, Colacino, Joseph M.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2016

Language:

english

File:

PDF, 754 KB

english, 2016

7

Characterization of monoclonal antibodies that specifically recognize the palm subdomain of hepatitis C virus nonstructural protein 5B polymerase

Paul Ingravallo, Frederick Lahser, Ellen Xia, Bruce Sodowich, Vicky C.H. Lai, Zhi Hong, Weidong Zhong

Journal:

Year:

2001

Language:

english

File:

PDF, 398 KB

english, 2001

8

Interim analysis of a 3-year follow-up study of NS5A and NS3 resistance-associated substitutions after treatment with grazoprevir-containing regimens in participants with chronic HCV infection

Lahser, Frederick, Galloway, Angela, Hwang, Peggy, Palcza, John, Brunhofer, Joann, Wahl, Janice, Robertson, Michael, Barr, Eliav, Black, Todd, Asante-Appiah, Ernest, Haber, Barbara

Journal:

Antiviral Therapy

Year:

2018

Language:

english

File:

PDF, 546 KB

english, 2018

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